Sugar acids and derivatives
Apexbio Technology LLC D-Pantethine 16816-67-4 25mg
D-Pantethine (16816-67-4) is a biologically-derived compound that functions as a precursor to coenzyme A via disulfide bond formation between two pantetheine molecules It is designed to participate directly in intermediary metabolic pathways including lipid and carbohydrate metabolism fatty acid beta-oxidation pyruvate processing and amino acid catabolism through its coenzyme A-related mechanisms D-Pantethine exerts its biological activity primarily through modulation of metabolic pathways Experimental studies typically employ cell-based assays or animal models examining enzyme activity and receptor modulation with reported IC50 values in the micromolar to submillimolar range depending on specific assay conditions and biological systems Based on these pharmacological properties D-Pantethine holds research potential in lipid-lowering effects anti-inflammatory processes neuroprotection and antiviral activity assessment
Medchemexpress LLC 4-Methylumbelliferyl-2-acetamido-2-deoxy-β-D-glucopyranoside | 37067-30-4 | MFCD00065481 | 99.9% | 379.36 | 50 MILLIGRAM
4-Methylumbelliferyl-2-acetamido-2-deoxy-β-D-Glucopyranoside is a fluorogenic substrate for N-acetyl-β-D-glucosaminidase. In vitro, the enzyme functionality is assessed by its ability to remove terminal β-glycosidically bound N-acetylglucosamine and N-acetylgalactosamine residues from this substrate.
- For research use only.
- Appears as a white to off-white solid.
- Soluble in DMSO at 50 mg/ml.
Medchemexpress LLC (D-His2,D-Trp6)-LHRH ((D-His2)-Triptorelin) | 321709-34-6 | 99.7% | 1311.45 | 10 MG
(D-His2,D-Trp6)-LHRH, also known as (D-His2)-Triptorelin, is a polypeptide identified through peptide screening. Peptide screening serves as a research tool for pooling active peptides, primarily using immunoassay. This technique is applicable for protein interaction studies, functional analysis, and epitope screening, particularly in agent research and development.
- Purity 99.71%
- Appearance as a solid
- Color white to off-white
- Soluble in DMSO up to 100 mg/mL (76.25 mM)
- Applicable for protein interaction studies
- Useful for functional analysis
- Supports epitope screening
Medchemexpress LLC 2-Propenamide, N-[2-[(5-chloro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]phenyl]- | 2513289-74-0 | C15H12ClN5O | 25 MG
BSJ-04-122 is a covalent MKK4/7 dual inhibitor that inhibits MKK4 and MKK7 with IC50 values of 4 nM and 181 nM, respectively. This compound is suitable for cancer research.
- Inhibits MKK4 with an IC50 of 4 nM
- Inhibits MKK7 with an IC50 of 181 nM
- Induces robust reduction of JNK phosphorylation at concentrations of 1, 5, and 10 μM within 6 hours
- Shows enhanced antiproliferative effects when combined with JNK-IN-8
Aobchem (2-Chloro-3-methoxyphenyl)(cyclopropyl)methanol | 95% | C11H13ClO2 | 500mg
(2-Chloro-3-methoxyphenyl)(cyclopropyl)methanol | 95% | C11H13ClO2 | 500mg
Medchemexpress LLC Guaiacylglycerol-bet 500mg
Guaiacylglycerol-beta-guaiacyl ether is a model compound of lignin monomers that can be degraded by Bacillus amyloliquefaciens CotA[1]
Medchemexpress LLC [D-Ala2]-GIP (human) | 444073-04-5 | 98.97% | 4983.60 | 25 MG
[D-Ala2]-GIP (human) is a GIP receptor agonist with an EC50 of 630 pM. It improves glucose tolerance and demonstrates neuroprotective activity in an MPTP-induced Parkinson's disease model. Additionally, it enhances cognitive function and hippocampal synaptic plasticity in obese diabetic rats. This product is suitable for research related to type 2 diabetes, Parkinson's disease, and similar conditions.
- Acts as a GIP receptor agonist with an EC50 of 630 pM
- Improves glucose tolerance by stimulating insulin release
- Demonstrates neuroprotective activity in MPTP-induced Parkinson's disease models
- Enhances cognitive function and hippocampal synaptic plasticity in obese diabetic rats
- Attenuates the behavioral phenotype of Parkinson's disease
- Reverses decline in motor ability and reduces muscle stiffness
- Inhibits the increase of MDA levels in the brain
Apexbio Technology LLC Beta-Lipotropin (1-10), porcine 77875-68-4 25mg
Beta-Lipotropin 1-10 porcine is an endogenous opioid peptide fragment derived from the N-terminal region of beta-lipotropin It is structurally related to opioid peptides and interacts with opioid receptors to mediate morphine-like activity within the central nervous system Beta-Lipotropin 1-10 porcine exerts its biological effects through modulation of opioid receptor signaling pathways Based on these pharmacological properties Beta-Lipotropin 1-10 porcine holds research potential in neuropharmacological studies particularly in investigations related to endogenous pain modulation neurotransmission mechanisms and opioid receptor ligand interactions
Medchemexpress LLC Cdk1/Cyc B-IN-1 | 2459916-56-2 | 98.5% | 353.85 | 5 MG
CDK1/Cyc B-IN-1 is a selective inhibitor of the CDK1/Cyc B complex, exhibiting an IC50 of 97 nM. This compound induces apoptosis and G2/M cell cycle arrest. It demonstrates broad-spectrum cytotoxic activity across various cancer cell lines.
- Selective CDK1/Cyc B complex inhibitor.
- IC50 of 97 nM against CDK1-Cyclin B.
- Triggers apoptosis.
- Induces G2/M cell cycle arrest.
- Exhibits broad-spectrum cytotoxic action against cancer cell lines.
- Shows cytotoxic activity against HCT-116 and WI-38 cells with IC50 values of 5.33 ± 0.69 μM and 21.69 ± 1.04 μM respectively.
